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Until recently, scientists studied gene expression by looking at only one or very few gene transcripts at a time Learn what gene expression measures, what techniques can be used, and what questions quantification of gene expression can answer. Research on changes in ge has increased for a number of reasons
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First, the number of clinical samples available from tissue repositories and the availability of new methods to measure ge from a variety of tissues are growing (shabihkhani et al., 2014). Expression profiling then tells the scientist which genes may play a role in obesity. First, different cells and tissues express a subset of genes as a direct consequence of cellular differentiation so many genes are turned off
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Second, many of the genes code for proteins that are required for survival in very specific amounts so many genes do not change.
The amount of data generated from these experiments is enormous. The researchers will use an approach called gene expression profiling to identify active and inactive genes in a cell or tissue
