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Over time, bones can become fragile and misshapen. La enfermedad de paget mamaria comienza en el pezón y se prolonga hacia el círculo oscuro de la piel (areola) que lo rodea. Paget's disease of bone often causes the body to produce too many blood vessels in the affected bones, increasing the risk of serious blood loss during an operation.
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Cuando la enfermedad ósea de paget ocurre en una zona en la que pasan nervios a través del hueso, como la columna vertebral o el cráneo, el sobrecrecimiento de los huesos puede comprimir y dañar los nervios, lo que provoca dolor, debilidad u hormigueo en el brazo o la pierna, o pérdida auditiva. La enfermedad de paget mamaria es una forma atípica de cáncer mamario Los medicamentos para la osteoporosis (bisfosfonatos) constituyen el tratamiento más común para la enfermedad ósea de paget
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Aunque en general los bisfosfonatos se administran por inyección en una vena, se pueden administrar por vía oral.
Bland ki, et al., eds Paget disease of the breast Comprehensive management of benign and malignant diseases Paget's disease of the breast is a rare form of breast cancer that affects the nipple
Paget's disease of the breast often causes scaly or crusty skin on the nipple. 用于诊断乳腺佩吉特病的检查和程序包括： 乳房检查。 医生将检查您的两侧乳房和腋窝淋巴结，通过触摸确定是否有肿块或其他异常。 乳腺 X 线摄影。 乳房 X 光检查是一种针对乳房的 X射线检查。乳房 X 光检查常被用来筛查乳腺癌。如果在乳房 X 光筛查时发现异常，医生可能会建议您接受诊断性. Most people with paget's disease of the breast have cancer within the breast tissue So you may have imaging tests to look at the breast tissue for signs of cancer.
